Lille moved to the top of the Ligue 1 Uber Eats table and Lyon are now their nearest challengers after Paris Saint-Germain's shock defeat at Lorient in Round 22.
PSG were 2-1 up in Brittany on Sunday after a brace of Neymar penalties but an 80th-minute equaliser from Yoan Wissa and a last-minute matchwinner from Nigeria international striker Terem Moffi gave struggling Lorient a surprise win.
"Today was an accident and we need to keep going," said PSG boss Mauricio Pochettino, who host another struggling side, Nîmes, in Wednesday's midweek round. "We've got another game Wednesday and it’s a good opportunity to play and perform better than today."
Lille took advantage of the champions' slip to move two points clear at the top of the table with Yusuf Yazici's first-half goal enough for them to beat Dijon at the Stade Pierre Mauroy.
WATCH: All the Round 22 highlights
"It's positive because we won, but the performance wasn't good," admitted captain Jose Fonte. "We need to do a lot better in everything, our passing, our calmness…We're going to work on that and do better in our next game."
That comes at Bordeaux on Wednesday where Jean-Louis Gasset's men will look to push another title contender after suffering a narrow 2-1 loss to Lyon on Friday.
Les Girondins, who had won their previous three league games, would have had a point after Samuel Kalu had equalised for the visitors, but Léo Dubois' stunning added-time winner took Lyon into second, a point clear of third-placed PSG.
"Winning like that, in added time, lets us believe that we can win every game," said OL centre-back Marcelo. "If we play like that every time, I'm sure we'll do great things at the end of the season."
Monaco have moved into fourth and are just three points behind PSG following their 2-1 victory at Nantes on Sunday evening, their fifth successive top-flight win.
WATCH: Léo Dubois provides the Moment of the Matchday
"You can believe me or not, but I'm first thinking about putting distance between us and sixth and seventh place," said the principality club's coach Niko Kovac, who saw a fourth goal in five games from defender Guillermo Maripan and a strike from the in-form Kevin Volland claim the points.
"We're focussed on that, and if we do it, we'll not be far from the podium. Each game is difficult in Ligue 1, you can win or lose. We've seen that with PSG this weekend, but we're not talking about the top three."
Neither are Rennes and Marseille, whose game at the Stade Vélodrome was called off following violent incidents at OM's training centre involving irate fans leaving the sides with a game in hand.
Metz and Lens continue to surprise as they beat Brest and Montpellier respectively to move into sixth and seventh, while Angers are in eighth following their 3-1 victory at home to Nîmes.
Charles Abi's goal was enough to give Saint-Etienne a 1-0 win over free-falling Nice, and Reims picked up a third victory in four as Dereck Kutesa's goal earned them the points at Strasbourg.